Grey's anatomy.

'' Too often, the thing you want most is the one thing you can't have. Desire leaves us heartbroken, it wears us out. Desire can wreck your life. But as tough as wanting something can be, the people who suffer the most are those who don't know what they want.''

Meredith: Are we fine?
Derek: Sure.
Meredith: Not convincing. I shouldn't have accused you of hovering. It wasn't nice. You were just trying to be there for me. But now I'm being available, and communicating, and getting naked, and doing all of your favorite things.
Derek: Good things.
Meredith: Then why are you still staring at the ceiling?
Derek: I don't ... I just ... that day you came out of the water ... trying to breathe for you. I love you, and I want you, but I don't know what to ... you didn't swim. You didn't swim and you know how to. And I don't know if I can ... I don't know if I want to keep trying to breathe for you.
Meredith: I should go. I'll go.

Meredith: I think it's better to have someone, even if it hurts, even if it is the most painful thing you have done, even if it's the most painful thing you've ever had to do. I think it's better to have someone.

Meredith:Forgive and forget. That’s what they say. It’s good advice, but it’s not very practical. When someone hurts us, we want to hurt them back. When someone wrongs us, we want to be right. Without forgiveness, old scores are never settled… old wounds never heal. And the most we can hope for, is that one day we’ll be lucky enough to forget.

Meredith: Change; we don’t like it, we fear it, but we can't stop it from coming. We either adapt to change or we get left behind. And it hurts to grow, anybody who tells you it doesn’t is lying. But heres the truth: the more things change, the more they stay the same. And sometimes, oh, sometimes change is good. Oh, sometimes, change is ... everything.

MEREDITH: "Some people believe that without history, our lives amount to nothing. At some point we all have to choose: do we fall back on what we know, or do we step forward to something new? It's hard not to be haunted by our past. Our history is what shapes us... what guides us. Our history resurfaces time after time. So we have to remember sometimes the most important history is the history we’re making today.

MEREDITH: "At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing where we all keep our distance and pretend not to care about each other, it's usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them. The people that are still with you at the end of the day, those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need."